WebPhenothiazines also possess peripheral adrenergic receptor blockade and quinidine-like cardiac effects. Phenothiazines may lower the seizure threshold. Clinical signs of toxicity … Web3. nov 1994 · The toxicity of phenothiazine Phenothiazine, the parent compound of a multitude of present-day drugs, has been employed on an extensive scale for its …
Phenothiazine poisoning in a goat. - CAB Direct
WebAcute toxicity LD50 Oral - Rat - male and female - 1,370 mg/kg(Phenothiazine) LD50 Dermal - Rat - male and female - > 2,000 mg/kg(Phenothiazine) (OECD Test Guideline 402) Skin corrosion/irritation Skin - Rabbit(Phenothiazine) Result: No skin irritation - 4 h (OECD Test Guideline 404) Serious eye damage/eye irritation Eyes - Rabbit(Phenothiazine) WebCentral Nervous System : The side effects most frequently reported with phenothiazine compounds are extrapyramidal symptoms including pseudo-parkinsonism, dystonia, dyskinesia, akathisia, oculogyric crises, opisthotonus, and hyperreflexia. [home.intekom.com] costituzione italiana da scaricare
Phenothiazine and butyrophenone intoxication in children
WebPhenothiazines also possess peripheral adrenergic receptor blockade and quinidine-like cardiac effects. Phenothiazines may lower the seizure threshold. Clinical signs of toxicity … WebPHENOTHIAZINE TOXICITY, EXTRAPYRAMIDAL SEIZURES, AND OCULOGYRIC CRISES By GEORGE PAULSON, M.D. Clinical Neuropharmacology Research Center, National institute … WebAbstract. Of 48 cases of phenothiazine poisoning that were analyzed, 34 were attributed to suicide attempts, nine to accidental ingestion, and five to drug reactions. As outpatient … costituzione italiana data entrata in vigore