WebMar 1, 2012 · RB1-inducible coiled-coil 1 (RB1CC1; also known as FIP200) plays important roles in several biological pathways such as cell proliferation and autophagy. Evaluation of RB1CC1 expression can provide useful clinical information on various cancers and neurodegenerative diseases. In order to realize the clinical applications, it is necessary to … WebRB1-inducible coiled-coil 1 (RB1CC1) is a nuclear DNA-binding protein that can induce RB1 (retinoblastoma 1) expression. RB1CC1 is abundantly expressed in human musculoskeletal and cultured osteosarcoma cells. The present study analyzed the expression of RB1CC1 and RB1 in osteosarcoma cells and in m …
Human Gene RB1CC1 (ENST00000435644.6) from GENCODE V43
WebDec 23, 2011 · RB1-inducible coiled-coil 1 (RB1CC1) functions in various processes, such as cell growth, differentiation, senescence, apoptosis, and autophagy. The conditional transgenic mice with cartilage-specific RB1CC1 excess that were used in the present study were made for the first time by the Cre-loxP syst … WebApr 12, 2024 · TRIM31, a member of the TRIM family, contains a N-terminal RING domain, a B-box domain, and two C-terminal coiled-coil (CC) domains . Especially, the RING domain perform as an E3 ubiquitin ligase and the deletion of RING domain can inhibit ubiquitination of TRIM31 itself or its substrate [ 34 ]. green compass rose
RB1CC1 - Sequence - nextprot.org
WebRb1-inducible coiled-coil 1 (Rb1cc1) expressed at high levels is associated with the maturation of human embryonic musculoskeletal cells. To clarify the molecular role of Rb1cc1 in muscular differentiation, we investigated the expression of Rb1cc1 and other genes that regulate differentiation in murine embryonic tissues and in C2C12 myoblasts. WebAutophagy is an evolutionarily conserved cellular process in which intracellular components are eliminated via lysosomal degradation to supply nutrients for organelle biogenesis and metabolic homeostasis. Flavivirus infections underlie multiple human diseases and thus exert an immense burden on public health worldwide. Mounting evidence indicates that … Webpresent study indicates that RB1CC1 together with hSNF5 and/or p53 enhances the RB1 pathway through transcriptional activation of RB1, p16 and p21. the 3'-untranslated region of RB1-inducible coiled-coil 1 gene is mutated in colon tumors. Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) flowtech exhaust tips